Sophie Le Coeur

Senior Researcher
lecoeur@ined.fr +33(0) 1 56 06 21 15 +33(0)1 56 06 21 94
Secretariat : Ornella Makiese +33 (0)1 56 06 20 24

Research field(s)

1) Impact of HIV/AIDS on mortality
- Impact on adult mortality
- impact on maternal mortality
- impact on sex differential mortality
- impact of antiretroviral therapy on mortality

2) Impact of HIV/AIDS on reproductive behaviors
and fertility

3) Consequences of preventive and care
interventions
- Prevention of mother-to-child transmission of
HIV: clinical trials PHPT-1, PHPT-2, PHPT-4 in
Thailand; psycho-social obstacles to mother to
child transmission in developing countries.
- Impact of antiretroviral treatments: cohort of
HIV-infected patients (adults and children)
treated with antiretrovirals in Thailand.

4) Economic consequences and the lives of HIV-
infected patients treated with antiretrovirals.

Research teams

Biographical and multi-level research group

International Perspectives research group

Mortality, Health and Epidemiology

Sexual and reproductive Health and Rights (Research team in partnership with Inserm - Univ Paris-Sud - UVSQ)

Research projects

Homosexualities: knowledge and methods

Sexual and Reproductive health at different life stages

Differential mortality and disparities in health

Hepatitis C, Hepatic cirrhosis and liver cancer

Demopæedia

Liens

Bibliography

A word by

Sophie Le Coeur answers our questions on World AIDS Day

Read the interview

Some publications

Le Cœur Sophie, Collins Intira, Pannetier Julie, Lelièvre Eva, 2009, « Gender and access to HIV testing and antiretroviral treatments in Thailand: why women have more and earlier access? », Social Science and Medicine, 6 (69), p. 846–853 (Special issue on “Women, children and AIDS care”)

Jourdain Gonzague, Le Cœur Sophie, Ngo-Giang-Huong Nicole et al. PHPT-3 study team, 2013, « CD4 Versus Viral Load Monitoring: A Randomized, Non-Inferiority Trial of Treatment Switching Strategies in HIV-Infected Adults in Thailand », Plos Medicine

Lelièvre Eva, Le Cœur Sophie, 2012, « Intergenerational Relationships within Families of HIV-infected Adults under Antiretroviral Treatment in Northern Thailand », Ageing and Society, 32 (4), p. 561-585

Lallemant Camille, Halembokaka Gaston, Baty Gaelle, Ngo-Giang-Huong Nicole, Barin Francis, Le Cœur Sophie, 2010, « Impact of HIV/Aids on Child Mortality before the Highly Active Antiretroviral Therapy Era: A Study in Pointe-Noire, Republic of Congo », Journal of Tropical Medicine, pii (897176)

Le Cœur Sophie, Khlat Myriam, Halembokaka Gaston, 2008, « Increased HIV infection rate among violent deaths: a mortuary study in the Republic of Congo », AIDS, 22 (13), p. 1675-1676

Collins Intira Jeannie, Jourdain Gonzague, Hansudewechakul Rawiwan, Kanjanavanit Suparat, Hongsiriwon Suchat, Gampiyasakul C., Sriminiphant Somboon, Technakunakorn Pornchai, Ngo-Giang-Huong Nicole, Duong Trinh, Le Cœur Sophie, Jaffar Shabbar, Lallemant Marc, Program for HIV Prevention and Treatment Study Team, 2010, « Long-term survival of HIV-infected children receiving antiretroviral therapy in Thailand: a 5-year observational cohort study », Clin Infect Dis., 51 (12), p. 1449-57

Briand Nelly, Le Cœur Sophie, Jourdain Gonzague, Hotrawarikarn Somboon, Sirinontakan Surat, Hinjiranandana Temsiri, Kanjanasing Annop, Traisathit Patrinee, McIntosh Kenneth, Lallemant Marc, Program for HIV Prevention and Treatment study group, 2010, « Haematological Safety of Perinatal Exposure to Zidovudine in Uninfected Infants Born to HIV-1 Infected Women in Thailand », AIDS Research and Human Retroviruses, 26 (10), p. 1163-1166